RUO • Provenance-first delivery

Clinical-grade bioinformatics operations, with enterprise-grade trust.

ForgeBio helps teams run production bioinformatics pipelines with explicit safety gates, audit-friendly outputs, and verifiable execution traceability from request to artifact.

ingest.validate → route.seqera → dispatch.run → poll.status → finalize.artifacts → gate.verify

Pipeline Provenance

Run-level traceability for every execution.

Safety Gates

Unverified output delivery blocked by default.

Provider Routing

Mock/non-mock route controls by lane.

RUO Posture

Research-use-only language and controls built in.

Platform

Ingest

Validate payloads, enforce schema and size constraints, normalize errors.

Orchestrate

Route by lane/provider, dispatch runs, poll, and finalize with retry policy.

Deliver

Serve artifacts/results only when lifecycle and verification gates are satisfied.

Use Cases

WES (GATK)

Operationalized with consistent validation, run tracking, and controlled artifact delivery.

RNA-seq (nf-core)

Operationalized with consistent validation, run tracking, and controlled artifact delivery.

PGx annotation

Operationalized with consistent validation, run tracking, and controlled artifact delivery.

Proteomics DIA

Operationalized with consistent validation, run tracking, and controlled artifact delivery.

Trust & Safety

  • • Verification-aware result gating (fail-closed outside allowed test contexts)
  • • Explicit provider auth/error taxonomy for operational clarity
  • • Structured run provenance summaries for audit and review
  • • RUO-safe presentation and language controls

Start a 2-week pilot

Choose one lane, validate operational flow end-to-end, and leave with reproducible execution, artifact traceability, and a clear go/no-go production checklist.